温馨提示
详情描述
gelsemine是什么意思，gelsemine翻译
Gelsemine, a natural alkaloid isolated from the Gelsemium sempervirens plant, has been the subject of extensive research due to its diverse pharmacological properties. This article aims to provide an overview of gelsemine, including its source, chemical structure, and its potential therapeutic applications.
Gelsemine is primarily found in the Gelsemium sempervirens plant, which is native to China, Japan, and other parts of Asia. The plant has been used in traditional Chinese medicine for centuries to treat various ailments, including snakebites, epilepsy, and mental disorders. The alkaloid gelsemine was first isolated from the plant in 1886 by a German chemist named Albert Neisser. The chemical structure of gelsemine was later elucidated in 1956 by a Japanese research team led by Yoshito Kishi.
Chemically, gelsemine is a bisbenzylisoquinoline alkaloid, consisting of a core structure with two benzyl groups attached to an isoquinoline ring. It also contains an oxindole ring and a lactone moiety. The chemical formula of gelsemine is C20H22N2O6, and it has a molecular weight of 394.45 grams per mole. The compound exhibits a yellow crystalline powder form and is soluble in chloroform and methanol but insoluble in water.
One of the most notable pharmacological properties of gelsemine is its ability to affect the central nervous system (CNS). The alkaloid has been found to have anxiolytic, neuroprotective, and anti