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isogenic是什么意思，isogenic翻译
Isogenic: A Synthetic Biology Breakthrough
The term "isogenic" refers to organisms or DNA sequences that have the same genetic background, save for a single gene or genetic element. In the context of synthetic biology, isogenic strains or systems are particularly valuable as they allow researchers to study the function of specific genes or genetic modifications in a controlled and comparative setting.
The significance of isogenic strains in scientific research cannot be overstated. They serve as powerful tools for understanding the intricacies of gene function, as well as for validating genetic modifications and screening for unintended consequences. By creating isogenic strains, researchers can effectively "knock out" or "knock in" specific genes, enabling them to study the impact of these changes on an organism's phenotype.
One of the most common applications of isogenic strains is in the field of genetic screening. Researchers can use isogenic strains to identify and characterize genes that are involved in particular biological processes or diseases. By comparing the phenotypes of isogenic strains with and without a specific genetic modification, researchers can gain insights into the function of the gene of interest.
In addition to traditional genetic screening methods, the advent of CRISPR
